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活性医薬品

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製品名 Diclofenac Sodium
product alias armiel, dichlorominic pain
CAS 15307-79-6
EINECS no 239-346-4
分子式 C14H18C12N2O
分子量 318.13
コンテンツ 98%
プロパティ colorless crystalline powder
融点 280-282
溶解性 soluble in polar organic solvents such as water and ethanol.

Diclofenac sodium is sold under the brand names Cambia, Cataflam, Voltaren, Voltaren-XR and Zipsor. These medications are used to help relieve the symptoms of rheumatoid arthritis, osteoarthritis, pain, 炎症, swelling, stiffness and joint pain. In some cases, this medication will be used as part of a treatment regimen for ankylosing spondylitis, menstrual cramps or acute migraine attacks.

Diclofenac sodium is available in enteric coated tablets, extended release tablets, capsules, powder or solution, liquid filled capsule or a traditional tablet form. Dosing and instructions will vary based on the condition that is to be treated. You should not take more than instructed as this can lead to an increased risk of side effects. If you are using this medication for arthritis, you will usually be ordered to take this medication once a day for up to two weeks or until you begin to feel better. It may take several weeks until you feel the full effects of the medication.

1. Diclofenac sodium Solaraze is a non-steroidal anti-inflammatory drug, which has obvious analgesic, anti-inflammatory and antipyretic effects. Through inhibiting the cyclooxygenase and blocking the synthesis of prostaglandin and produce analgesia, anti-inflammatory, antipyretic effect.

2. Diclofenac sodium Solaraze has good anti-inflammatory and analgesic effects, can significantly relieve the following symptoms and effectively improve the function: pain at rest, pain during exercise, morning stiffness, joint edema.

3. Diclofenac sodium Solaraze can relieve rheumatoid arthritis and osteoarthritis. Spinal joint disease, gouty arthritis, rheumatoid arthritis and other chronic arthritis of the acute onset or persistent joint swelling pain symptoms. All kinds of soft tissue rheumatic pain, such as shoulder pain, tenosynovitis, bursitis, myalgia and post-exercise injury pain, 等. Acute mild to moderate pain such as: pain after surgery, trauma, strain, primary dysmenorrhea, toothache, headache, 等.

アイテム 標準 結果
特性 Pure white crystalline powder, わずかに

hygroscopic

適合
溶解性 Sparingly soluble in water, freely soluble in methanol, エタノール (96%); アセトンにわずかに溶ける;エーテルに実質的に不溶 適合
識別する (あ) IR-Spectrum (あ)適合する
(B) Reaction of sodium salt (B)ポジティブ
PH 6.5~7.5 7.13
溶液の外観 クリア 適合
Absorption of sodium salt≤0.05 0.015
関連物質 Single impurity ≤0.2% 適合
総不純物 ≤0.5%
重金属 ≤10ppm 適合

 

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