ŠT. CAS: 148031-34-9
Test: 98.5% min.
Ocena: Farmacevtski razred
Shranjevanje: Shranjujte v tesnem, svetlobno odporne posode, hranimo v hladilniku(2-8° C)
Molekularna formula: C35H49N11O9S2
Molekulska teža: 831.96
Videz: Bel prah
Zaporedje: Mpr-Harg-Gly-Asp-Trp-Pro-Cys)-NH2
Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the so-called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.
1 . Eptifibatide is used to reduce the risk of acute cardiac ischemic events (smrt in/ali miokardni infarkt) pri bolnikih z nestabilno angino pektoris ali brez dviga veznice ST (npr., brez zobca Q) miokardni infarkt (tj., akutni koronarni sindromi brez elevacije ST spojnice) tako pri bolnikih, ki bodo prejeli nekirurški poseg (konzervativen) zdravljenje in tisti, ki so podvrženi perkutanemu koronarnemu posegu (PCI).
2 .treat the adults and the children above6 years old chronic humanity flaw virus(HIV)infects. chronic humanity flaw virus(HIV)infects.
