Estradiol Valerate is the parenterally-administered synthetic valerate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. This agent exhibits mild anabolic and metabolic properties, and increases blood coagulability.
Estradiol Valerate is used by women to help reduce symptoms of menopause (ホットフラッシュなどの, 膣の乾燥). これらの症状は、体内でのエストロゲンの生成が減少することによって引き起こされます. この薬は、十分なエストロゲンを生成できない女性にも使用できます。 ( 例えば, 性腺機能低下症のため, 原発性卵巣不全) and by men to treat prostate cancer.
1.Estradiol valerate is anti estrogen steroids which is used in Hormone Replacement Therapy in postmenopausal women who have had a hysterectomy Estradiol valerate contains a hormone which is similar to the hormone oestrogen that is produced by the body . When women go through the menopause , levels of oestrogen become low . This leads to symptoms such as hot flushes , night sweats and dryness of the vagina . Estradiol valerate helps to replace the low levels of oestrogen which may help to relieve the symptoms of the menopause . This is known as hormone replacement therapy .
2.Estradiol valerate is a female estrogen hormone . It works by replacing natural estrogens in a woman who can no longer produce enough estrogen . It works for advanced prostate cancer by antagonizing male hormones . Treating certain symptoms of menopause ( eg , ほてり , vaginal itching , 燃焼 , or dryness ) . It is used to treat low levels of estrogen caused by certain conditions . It may be used to treat certain types of prostate cancer ( advanced androgen dependent ) . 医師の判断に応じて、他の症状にも使用できる場合があります。.