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Aktive legemidler

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Produktnavn Ethacridine Lactate Monohydrate / Rivanol
Cas number 6402-23-9
Molekylformel C15H15N3O.C3H6O3.H2O
Molekylvekt 361.4
Utseende yellow powder
Smeltepunkt 243-245 °C(tent.)

Rivanol is the lactate-hydrate of α-ethoxy-6,9-diaminoacridine. It is a bactericidal preservative for external use and has a strong killing effect on gram-positive bacteria and a few gram-negative bacteria. , Has good antibacterial effect on cocci, especially streptococcus, and has strong activity in alkaline environment. This product is small in irritation, and the therapeutic concentration does not damage the general tissues, but it can stimulate the contraction of uterine smooth muscle, soften and relax the cervix. Derfor, it can be used to induce labor in women's mid-term pregnancy without obvious side effects.

1. Disinfection: Ethacridine Lactate Monohydrate is a disinfectant and antiseptic that inhibits the growth of Gram-positive bacteria, especially cocci. The solution can be used for the disinfection of small, lightly traumatised wounds and infected wounds. It can cause burning sensation, allergy, rash, itching and other adverse reactions.

2. Bactericidal: Ethacridine Lactate Monohydrate is disinfectant and bactericidal and can be used externally as a cream to disinfect small wounds on the skin surface. Occasionally there are allergic reactions.

3. Induction of labour in mid pregnancy: Ethacridine Lactate Monohydrate Injection is commonly used to induce labour in mid pregnancy by injecting a concentration into the amniotic cavity to cause sterile inflammation, stimulate uterine contractions and expel the foetus.

PUNKT SPESIFIKASJON RESULTATER
Beskrivelse Gult krystallinsk pulver; odourless

Soluble in hot water, soluble in boiling anhydrous ethanol, lett løselig i vann, lett løselig i etanol, insoluble in ether

Overholder
Identifikasjon Consistent with the

Pharmacopoeia (1,2,3,4)

Overholder
PH 6.0-7.0 Overholder
Klorid(Cl) The general principles of the pharmacopoeia 0801 Overholder
Sulfat(SO4) The general principles of the

pharmacopoeia 0802

Overholder
Beslektet stoff The general principles of the

pharmacopoeia 0512

Overholder
Tap ved tørking The general principles of the pharmacopoeia 0831

4.5%-5.5%

Overholder
ignition residue The general principles of the pharmacopoeia 0841

≤0,1 %

0.08%
Tungmetaller The general principles of the pharmacopoeia 0821

≤30 ppm

Overholder
Assay The general principles of the pharmacopoeia 0710 99.3%
Konklusjon Conform to Chinese Pharmacopoeia 2015

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