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Farmaceutische peptiden

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Productnaam:Fertirelin Acetate
Synoniemen: Luteinizinghormone-releasing factor,LH-RH
CAS-nr.: 66002-66-2
Moleculaire formule: C57H80N16O14
Moleculair gewicht: 1213.37 g/mol
Zuiverheid: 99%min
Verschijning: Wit poeder

Fertirelin is a synthetic luteinizing hormone-releasing hormone (LH-RH) analogue, and it is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.

Fertirelin was administered at the beginning of the protocol followed 7 days later by 500 μ G cloprosterol. Two days later, a second dose of fertirelin was given and AI performed 16-19 h later regardless of the incidence of behavioral oestrus. The conception rate did not differ between the 50 μ G fertirelin group (61.1%; N = 72) and the 100 μ G group.

1)To supplement LH in cases of ovulation failure.
2)To induce lactation post partum.
3)Management of genital hypoplasia and reduced libido in males.
4)To manange signs of estrus in ferrets.

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