製品名:Gestonoronacetat / Gestonorone Acetate
CAS:31981-44-9
同義語:17-Hydroxy-19-norpregn-4-ene-3,20-dione 17-acetate；17alpha-Hydroxy-19-norprogesterone-17alpha acetate；19-Nor-17alpha-hydroxyprogesterone acetate,Norhydroxyprogesterone Acetate
分子式:C22H30○4
分子量:358.47
アイネックスNo.:250-882-8
密度:1.16g/cm3
融点:228-230℃
Gestonorone acetate, or gestronol acetate, also known as norhydroxyprogesterone acetate, is a progestin of the 19-norprogesterone and 17α-hydroxyprogesterone groups which was developed in the early 1960s but was never marketed.
Gestonorone acetate has been found to consistently inhibit ovulation at an oral dosage of 10 mg/day in combination with 50 μg/day oral ethinylestradiol.Weak or no endometrial effects were observed at an oral dosage of 100 mg/日, basal vacuoles appeared at 130 に 140 mg/日, and full endometrial secretory transformation occurred at 220 mg/日.
| TEST ITEMS |
仕様 |
結果 |
| 説明 |
White or Almost White Crystalline Powder |
白い粉 |
| 識別 |
A.B. |
ポジティブ |
| アッセイ |
97.0～103.0% |
99.1% |
| 乾燥減量 |
1.0%最大 |
0.25% |
| 融点 |
222~228°C |
227℃ |
| Organic Volatile Impurities |
meets the requirement. |
適合 |
| 関連物質 |
meets the requirement. |
適合 |
| 残留溶媒 |
meets the requirement. |
適合 |
| 粒子サイズ |
100%20 microns |
適合 |
| 結論 |
The specification conform with USP30 standard |
