製品名:J-147
CAS:1146963-51-0
外観:白い粉
MF:C18H17F3N2O2
分子量:350.33
純度:99%
ストレージ:涼しく保ちます, ドライ, 密閉した容器またはシリンダー内の暗い場所
J 147 is a novel neurotrophic drug for cognitive enhancement and Alzheimer's disease. J 147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer's disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques.