Jinyang Base CAS:175-86-0

It is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18-64 years old. works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, was initially created as an antidepressant. Cependant, unlike other SSRIs, is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.

It is as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. is a selective 5 - HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders.

This ingredients belongs to phosphodiesterase type 5 of this kind of inhibitor. When sexuelle erregung, neurone of NANC and nitrogen oxide in endothelial cells synthase and catalyse L-arginine to synthetize nitrogen oxide, which activate guanosine to synthesis increase, then lead cavernous body of penis smooth muscle and artery of penis into relaxation, blood into penis sponge sinus, make penis erect.