Lubiprostone is a white crystalline powder, easily soluble in ether and ethanol, and almost insoluble in water.
Lubiprostone is a localized chloride channel activator, which can selectively activate type 2 chloride channels located on the luminal cell membrane at the tip of the gastrointestinal epithelium, increase the secretion of intestinal juice and the motility of the intestine, thereby increasing defecation, Alleviates symptoms of chronic idiopathic constipation without altering plasma sodium and potassium concentrations.
Lubiprostone is used to relieve stomach pain, 膨満感, and straining and produce softer and more frequent bowel movements in people who have chronic idiopathic constipation (便の排出が困難またはまれであり、それが長期間続くこと 3 病気や薬が原因ではなく、数か月以上続いている).
