CAS: 6533-00-2
Formule: C21H28O2
Poids moléculaire: 312.45
Synonymes: 13-Ethyl-17A-ethynyl-17b-hydroxy-4-gonen-3-one; DL-Norgestrel; Methylnorethindrone; A-Norgestrel;
EINECS: 229-433-5
Densité: 1.139 g/cm3
Point de fusion: 239-241 °C(lit. )
Point d'ébullition: 459.139 °C à 760 mmHg
Point d'éclair: 195.446 °C
Apparence: Solide blanc
Pureté: 99%
Norgestrel binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like Norgestrel will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone)
Norgestrel, a synthetic progesterone analog , is a racemic mixture of which levonorgestrel is the biologically active component. Levonorgestrel prevents pregnancy by inhibiting ovulation and by causing the cervical mucous to thicken, which makes it harder for sperm to move toward the uterus.
Norgestrel is used to prevent pregnancy. On l'appelle souvent le "mini pilule" car il ne contient aucun œstrogène. Norgestrel (une forme de progestatif) is a hormone that prevents pregnancy by changing the womb and cervical mucus to make it more difficult for an egg to meet sperm (fertilisation) or for the fertilized egg to attach to the wall of the womb (implantation). Regular use of the "mini pilule" prevents the release of an egg (ovulation) in about half of the women who use it.Norgestrel is usually used by women who cannot take estrogen. For the most effective results, it is very important to take this medication exactly as prescribed.
You will take your first pill on the first day of your period or on the first Sunday after your period begins. You may need to use back-up birth control, such as condoms or a spermicide, when you first start using this medication. Follow your doctor's instructions.
Take one pill every day, no more than 24 hours apart. When the pills run out, start a new pack the following day. You may get pregnant if you do not take one pill daily. Get your prescription refilled before you run out of pills completely.
The 28 day birth control pack contains seven "reminder" pills to keep you on your regular cycle. Your period will usually begin while you are using these reminder pills.