Scopolamin hydrobromide is the hydrobromide salt of the anticholinergic natural product Scopolamin, isolated from plants of the Solanaceae family. Scopolamin exhibits anticholinergic properties through competitive inhibition of acetylcholine muscarinic receptors with selectivity for mAChR M1. Suppression of the cholinergic response results in decreased activity of the parasympathetic nervous system, widely exploited in studies concerning parasympathetic functioning.
Scopolamine Hydrobromide is pharmceutical material for peripheral anticholinergic drugs which can smooth muscle spasm, ease the gastrointestinal tract, bile duct and urinary tract and inhibit peristalsis. It applies to the stomach, duodenum, colon fiber endoscopic examination as the operative peparation, so it can be used for the treatment of gastrointestinal spasm, biliary Colic, renal colic or gastrointestinal peristalsis, such as hyperthyroidism.
1. This product is a peripheral role stronger anticholinergic activity, blocking M choline receptor.
2. This product is peripheral role of atropine strong and maintain time is short, the respiratory center a cordial, central role to suppress give priority to.
3. Can restrain glands secretion, remove capillary vessel spasm, improve microcirculation, dilated bronchi, remove smooth muscle convulsion.
4. On the brain sedative and hypnotic effects, the respiratory center a cordial.
