Thymopentin acetas est biologice activum peptidis maxime secreta ab epithelialibus cellulis corticis thymici et medulla.. acetas thymopentin est agens immunomodulatorium efficax cum brevi plasmate semianimi vitae 30 seconds. Aceta thymopentin auget generationem T-cellulae ex cellulis embryonis humano derivatis (heSCs *).
Thymopentin is a five amino acid peptide fragment of thymopoietin that exhibits immunostimulatory and anticancer activities. Thymopentin decreases iNOS activity in the treatment of Sezary Syndrome, a severe form of lymphoma. In leukemia cells, thymopentin inhibits proliferation and colony formation and induces differentiation. In macrophages, thymopentin increases pro-inflammatory cytokine secretion, activation of NF-κB, production of HSP72, and signaling by JNK. Thymopentin shows clinical benefit when used as an adjuvant, improving the response rate in subjects administered hepatitis B vaccines.
