Ursodeoxycholic acid is a chemical preparation of natural bile acid isolated from bear bile. It is an epistereoisomer of chenodeoxycholic acid. Short and small dose. It exists in bile in combination with taurine in the body, is a hydrophilic bile acid, and is a cholesterol gallstone dissolving agent. It can reduce the secretion of cholesterol by the liver, reduce the saturation of cholesterol in bile, promote the secretion of bile acid, increase the solubility of cholesterol in bile, dissolve cholesterol stones or prevent the formation of stones. It can increase the amount of bile secretion, relax the sphincter of the bile duct orifice to produce a choleretic effect, which is beneficial to the discharge of stones. This product does not dissolve other types of gallstones. Ursodeoxycholic acid is suitable for the treatment of cholesterol stones, hyperlipidemia, disorders of bile secretion, primary biliary cirrhosis, chronic hepatitis, bile reflux gastritis and the prevention of acute rejection and reaction of liver transplantation. The stone-dissolving effect of this product is slightly weaker than that of chenodeoxycholic acid.
Ursolic acid is a triterpenoid compound present in natural plants. It has various biological effects such as sedation, anti-inflammatory, antibacterial, anti-diabetic, anti-ulcer, and lowering blood sugar. Ursolic acid also has obvious antioxidant function. 加えて, ursolic acid can also exhibit its anticancer activity by inducing apoptosis, inhibiting cell cycle progression, inhibiting cell proliferation, inhibiting metastasis, and reducing tumorigenesis through various signaling pathways.
