Kemijsko ime: Acetildenafil
CAS: 831217-01-7
Sopomenke: Hongdenafil;Acetildenafil;Acetildenafil (Hongdenafil);5-[2-Ethoxy-5-[2-(4-ethyl-piperazin-1-yl)-acetyl]-fenil]-1-Methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyriMidin-7-one;5-[2-Ethoxy-5-[2-(4-ethyl-1-piperazinyl)acetyl]fenil]-1,6-dihydro-1-methyl -3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one;7H-Pyrazolo[4,3-d]pyriMidin-7-one,
Molekularna formula: C25H34N6O3
Teža formule: 466.583
Test: 99%
MP: 131-133°C
Temp. shranjevanja: Refrigerator
Kemijske lastnosti: Off-White to Pale Yelow Solid
Uporaba: Acetildenafil is a drug used to treat erectile dysfunction (impotence) in males and pulmonary arterial hypertension (PAH).
Acetildenafil is a synthetic drug which is known to act as a phosphodiesterase inhibitor. It is an analogue of sildenafil (Viagra) and appears to boost libido and alleviate erectile dysfunction. Since, Acetildenafil inhibits phosphodiesterase enzyme, it can be used to regulate intracellular levels of the second messengers cAMP and cGMP, and cell function.
Despite such promising effects of this substance, Acetildenafil remains a research chemical, majorly used by researchers from across the world to conduct scientific experiments. No thorough testing on the above mentioned effects of acetildenafil have been conducted so far. Scientists can conduct research on this potential chemical to know more about its beneficial uses.
- It may act as an inhibitor of Phosphodiesterase
Acetildenafil may inhibit Phosphodiesterase 5, which means it could block the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) na ciklični GMP, ki je prisoten v gladkih mišičnih celicah krvnih žil, ki oskrbujejo moške spolne organe s krvjo. Pred kratkim, Acetildenafil so odkrili v številnih zeliščnih afrodiziakih brez recepta.
Vazodilatatorji so sintetična zdravila, ki se uporabljajo za širjenje krvnih žil, zato povzročijo zmanjšanje žilnega upora in povečan pretok krvi. Z nadaljnjimi raziskavami o učinkih acetildenafila in njegovih analogov na krvne žile, raziskovalcem bo omogočil razumeti, kako bi lahko bil koristen za zdravljenje hipertenzije, pri čemer ima bolnik visok krvni tlak in kongestivno srčno popuščanje.
- Deluje kot urološko sredstvo
Urološka zdravila so zdravila, ki se uporabljajo pri zdravljenju urogenitalnih stanj, kot je urinska inkontinenca, erectile dysfunction and prostatic hyperplasia. Acetildenafil acts as urological agent because it inhibits the enzyme - phosphodiesterase type 5 (PDE5). Blocking PDE5 promotes the development and maintenance of male genital stimulation.
