Brimonidin je visoko selektiven zaviralec receptorjev α2, uspešno razvilo ameriško podjetje Allergan, ki je zdravilo za oči. Lahko zmanjša intraokularni tlak (IOP). Očesna raztopina brimonidinijevega tartrata, ki se prodaja na trgu, je oblika brimonidinijevega tartrata, ki je dobro zdravilo za zniževanje očesnega tlaka pri zdravljenju kroničnega glavkoma z odprtim zakotjem in očesne hipertenzije, ampak tudi za ravni IOP z argonskim laserjem.
Brimonidine tartrate ophthalmic solution has a dual mechanism of action by reducing aqueous humor production and increasing the pigment layer of liquid scleral outflow therapeutic purposes. After dropping into the eye, the effect is rapid, and it can reach the peak when using up to 2h, and the effective time can maintain 12h. Blood can only detect traces of drugs. This product has first-pass metabolism in the liver, and metabolites excreted in the urine by the kidneys. Systemic absorption and distribution are not affected, and the elderly do not need dose adjustment.
Brimonidine is a medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. This drug increases fluid draining from the eye and lowers the amount of fluid made in the eye. Brimonidin spada v skupino zdravil, imenovanih alfa agonisti. Brimonidin je generično zdravilo, ki se prodaja tudi pod blagovnima znamkama Mirvaso in Alphagan. To zdravilo je na voljo že leta. Pri zdravljenju glavkoma odprtega zakotja in očesne hipertenzije, uporaba brimonidina je pogosta.
