Latanoprost is a new phenyl substituted propyl ester prostaglandin F2a, which is a selective F2a receptor agonist. It is an inactive substance that can quickly penetrate into the cornea. It can be hydrolyzed into active free acids in cornea and plasma. It can increase the outflow of aqueous humor through the canthus layer. The dosage is small, but it can promote the filling of aqueous humor. The liquid medicine can penetrate into the upper layer of ciliary choroid on the eyeball, and has a good effect of reducing intraocular pressure.
Očesna raztopina latanoprosta je zdravilo, ki se daje v oči za nadzor napredovanja glavkoma ali očesne hipertenzije z zmanjšanjem intraokularnega tlaka. Je analog prostaglandinov (natančneje analog prostaglandina F2α) ki znižuje pritisk s povečanjem odtoka vodne tekočine iz oči skozi uvealno-čistni trakt. Latanoprost je predzdravilo izopropilnega estra, kar pomeni, da je neaktiven, dokler ga esteraze v roženici ne hidrolizirajo v biološko aktivno kislino..
