Estron (E1, in tudi estron) je estrogenski hormon, ki ga izločata jajčnik in maščobno tkivo s kemijskim imenom 3-hidroksiestra-1,3,5(10)-trien-17-on in kemijsko formulo C18H22O2. Estron je brez vonja, trdni kristalni prah, bele barve s tališčem 254.5 °C in specifično težo 1,23. Estron je eden od več naravnih estrogenov, ki vključujejo tudi estriol in estradiol. Estrona je med tremi hormoni najmanj; Estradiol je skoraj vedno prisoten v reproduktivnem ženskem telesu, in estriola je v izobilju predvsem med nosečnostjo.
Estrone is known to be a carcinogen for human females as well as cause breast tenderness or pain, slabost, glavobol, hipertenzija, and leg cramps. Pri moških, estrone has been known to cause anorexia, slabost, bruhanje, and erectile dysfunction.Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women.
Mainly used for uterine hypoplasia, menstrual disorders and menopausal disorders. It is an intermediate for the synthesis of ethinyl estradiol drugs. Can cause nausea, bruhanje, dizziness, itd. Prolonged use can cause excessive endometrial hyperplasia and bleeding.This product is the intermediate of ethinyl estradiol, a hormone drug used in the No. 1 contraceptive.Biochemical research, estrogenska zdravila. Je intermediat za sintezo etinilestradiola.
