Synonyma: (DES-GLY10, PRO-NHET9)-LHRH;[DES-GLY10] LH-RH, ETHYL AMIDE
CAS NO.: 38234-21-8
EINECS No.:636-807-5
Formulae hypotheticae: C55H76N16O12
M. Pondus: 1153.29 g / mol
Puritas: 99%min
Aspectus: cerussa
Fertirelin synthetica luteinizing hormone solvens hormone (LH-RH) analogon, et est potens LHRH agonist. Post transitum incremento, continua administratio consequitur in downregulatione gradus LH et FSH, quam sequitur suppressio biosynthesis steroidis ovarii et testium..
Fertirelin administrabatur initio protocolli sequentis 7 post dies by 500 μ G cloprosterol. Biduo post, secunda dosis fertirelini, dato AI 16-19 h later regardless of the incidence of behavioral oestrus. The conception rate did not differ between the 50 μ G fertirelin group (61.1%; N = 72) and the 100 μ G group.
Mainly has a strong angiotensin II vasoconstriction and increase in blood pressure. The mechanism is: 1. So that the body arteriole smooth muscle contraction, increased peripheral resistance; 2. So increase the release of adrenal aldosterone, causing sodium retention, increased blood volume; 3. Directly contribute to renal tubular sodium and water reabsorption; 4. So the brain central nervous sympathetic vasoconstrictor activity, causing increased peripheral vascular resistance; 5. Stimulate the adrenal medulla to release epinephrine and norepinephrine.
| Puritas (HPLC) |
99.0% |
| Aspectus |
Pulvis albus |
| una immunditia(HPLC) |
1.0% |
| Amino Acidum Compositio |
10% theoretical |
| Peptide Content(N%) |
80%(by %N) |
| Aqua Content(Carolus Fischer) |
6.0% |
| Acetate Content(HPIC) |
15.0% |
| MS(ESI) |
|
| Massa Libra |
95.0～105.0% |
