Synonyma: (DES-GLY10, PRO-NHET9)-LHRH;[DES-GLY10] LH-RH, ETHYL AMIDE
CAS NO.: 38234-21-8
EINECS No.:636-807-5
Formulae hypotheticae: C55H76N16O12
M. Pondus: 1153.29 g / mol
Puritas: 99%min
Aspectus: cerussa
Fertirelin synthetica luteinizing hormone solvens hormone (LH-RH) analogon, et est potens LHRH agonist. Post transitum incremento, continua administratio consequitur in downregulatione gradus LH et FSH, quam sequitur suppressio biosynthesis steroidis ovarii et testium..
Fertirelin administrabatur initio protocolli sequentis 7 post dies by 500 μ G cloprosterol. Biduo post, secunda dosis fertirelini, dato AI 16-19 h postea pro incidentia oestri se gerendi. Conceptio rate non differunt inter 50 m G fertirelin group (61.1%; N = 72) et " 100 m G group.
Maxime fortis angiotensin II vasoconstriction et incremento sanguinis pressura. Mechanismus est: 1. Ut corpus arteriolum contractio musculus lenis, auctus resistentia periphericis; 2. Auge igitur emissionem aldosterone adrenalis, sodium retention causing, auctus sanguine volumine; 3. Directe conferunt ad sodium renum tubi et aquae reabsorptionis; 4. Itaque centrum cerebri nervosi vasoconstrictoris sympathetici activitatem, causando augeri periphericis vascularium resistentia; 5. Medulla adrenalis incitare ad emissionem epinephrinam et norepinephrinem.
| Puritas (HPLC) |
99.0% |
| Aspectus |
Pulvis albus |
| una immunditia(HPLC) |
1.0% |
| Amino Acidum Compositio |
10% theoretical |
| Peptide Content(N%) |
80%(by %N) |
| Aqua Content(Carolus Fischer) |
6.0% |
| Acetate Content(HPIC) |
15.0% |
| MS(ESI) |
|
| Massa Libra |
95.0～105.0% |
