Название продукта:Flutamide
КАС:13311-84-7
МФ:C11H11F3N2O3
МВт:276.21
ЭИНЭКС:236-341-9
член парламента:112 °С
Flutamide is a kind of synthetic, non-steroidal antiandrogen which is mainly used for the treatment of prostate cancer. It is a kind of toluidine derivative and a nonsteroidal antiandrogen with a similar structure of bicalutamide and nilutamide. The mechanism of its anti-cancer property is through acting as a selective antagonist of the androgen receptor (АР).
Flutamide belongs to a class of drugs known as anti-androgens . Testosterone is a natural hormone, helps prostate cancer to grow and spread. Flutamide works by blocking the effects of testosteron, thereby slowing the growth and spread of prostate cancer.
| Предметы |
Стандартный |
| Характеристики |
Бледно-желтый кристаллический порошок |
| Идентификация |
А:ИК-поглощение
Б:ВЭЖХ |
| Диапазон плавления |
110-114ºС( does not exceed 2ºC) |
| Потери при высыхании |
Не более чем 0.5% |
| Остаток при зажигании |
Не более чем 0.1% |
| Родственные соединения |
4-Nitro-3-trifluoro-methylacetanilide:
НМТ: 0.2% |
4-Nitro-3-trifluoro-methylaniline:
НМТ: 0.15% |
|
НМТ: 0.2% |
| 4-Nitro-3-trifluoromethylpropionanilide: НМТ: 0.3% |
3-trifluoromethylisobutyranilide:
НМТ: 0.2% |
| o-Flutamide:НМТ: 0.2% |
Unknown(relative response:1.0) :
НМТ: 0.05% |
| Total unknown:НМТ: 0.1% |
| Всего примесей:НМТ: 0.4% |
| Остаточные растворители |
Meth anol:НМТ:3000ppm |
| Растворимость |
Freely soluble in acetonemia
soluble in chloroformate other practically
insoluble mineral oil.
и вода |
| Тяжелые металлы |
Not more than10ppm |
| Анализ |
98.0-101.0%
(calculated on the dried basis) |
