نام محصول:Flutamide
CAS:13311-84-7
MF:C11H11F3N2O3
مگاوات:276.21
EINECS:236-341-9
نماینده مجلس:112 درجه سانتی گراد
Flutamide is a kind of synthetic, non-steroidal antiandrogen which is mainly used for the treatment of prostate cancer. It is a kind of toluidine derivative and a nonsteroidal antiandrogen with a similar structure of bicalutamide and nilutamide. The mechanism of its anti-cancer property is through acting as a selective antagonist of the androgen receptor (AR).
Flutamide belongs to a class of drugs known as anti-androgens . Testosterone is a natural hormone, helps prostate cancer to grow and spread. Flutamide works by blocking the effects of testosteron, thereby slowing the growth and spread of prostate cancer.
| موارد |
استاندارد |
| خصوصیات |
Pale yellow crystalline powder |
| شناسایی |
الف:IR Absorption
ب:HPLC |
| محدوده ذوب |
110-114ºC( does not exceed 2ºC) |
| ضرر در خشک شدن |
نه بیشتر از 0.5% |
| باقی مانده در احتراق |
نه بیشتر از 0.1% |
| ترکیبات مرتبط |
4-Nitro-3-trifluoro-methylacetanilide:
NMT: 0.2% |
4-Nitro-3-trifluoro-methylaniline:
NMT: 0.15% |
|
NMT: 0.2% |
| 4-Nitro-3-trifluoromethylpropionanilide: NMT: 0.3% |
3-trifluoromethylisobutyranilide:
NMT: 0.2% |
| o-Flutamide:NMT: 0.2% |
Unknown(relative response:1.0) :
NMT: 0.05% |
| Total unknown:NMT: 0.1% |
| کل ناخالصی ها:NMT: 0.4% |
| حلال های باقیمانده |
Meth anol:NMT:3000ppm |
| حلالیت |
Freely soluble in acetonemia
soluble in chloroformate other practically
insoluble mineral oil.
and water |
| فلزات سنگین |
Not more than10ppm |
| سنجش |
98.0-101.0%
(calculated on the dried basis) |
