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向知性薬

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製品名:Galantamine Hydrobromide
別名: ガランタミンHBr,5-メトキシ-9-メチル-2,3,3a,3a1,8,9,10,11-オクタヒドロ-4-オキサ-9-アザシクロオクタ[確かに]フルオレン-2-オール臭化水素酸塩(ガランタミン臭化水素酸塩)
外観:白い粉
CAS:69353-21-5
MF:C17H22BrNO3
M.W.:368.27
仕様:99%

Galanthamine Hydrobromide is the anti-cholinesterase, weak effect. It has strong effect to the central nervous system through the blood brain barrier. It mainly cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, 等. It also can be applied to puerilism, posttraumatic apoplexy, polyneuritis and radiculitis.Clinic function: mainly used in myasthenia gravis, poliovirus quiescent stage and sequela, also in polyneuritis, funiculitis and sensorimotor barrier caused by nervous system disease or traumatism. It's major used in Alzheimer's disease, has the principal function for dement and dysmnesia caused by organic brain damage.

Galantamine Hydrobromide is the hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically or naturally from the bulbs and flowers of Narcissus and several other genera of the Amaryllidaceae family with anticholinesterase and neurocognitive-enhancing activities. Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing the concentration and enhancing the action of acetylcholine (Ach). 加えて, galantamine is a ligand for nicotinic acetylcholine receptors, which may increase the presynaptic release of Ach and activate postsynaptic receptors. This agent may improve neurocognitive function in mild and moderate Alzheimer' s disease and may reduce abstinence-induced cognitive symptoms that promote smoking relapse.

1.Galantamine hydrobromide powder is weak anticholinesterase drug through the blood-brain barrier, it is the role of the central nervous system.

2.Galantamine hydrobromide powder can make the neuromuscular recovery and improve the state of paralysis of various peripheral neuromuscular disorders.

3.Galantamine hydrobromide powder can treatment of a wide range of less toxic, and are well tolerated by patients.

4.Galantamine hydrobromide powder is mainly used in clinical treatment of sequelae of poliomyelitis (polio), muscular dystrophy and myasthenia gravis.

5.Galantamine hydrobromide powder can also be used for children with cerebral palsy, traumatic sensorimotor disorder, polyneuritis and radiculitis etc.

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