Galantamín hydrobromid je anticholínesteráza, slabý účinok. Má silný účinok na centrálny nervový systém cez hematoencefalickú bariéru. Lieči najmä následky detskej obrny, sweeny a myasthenia gravis pseudoparalytica, atď. Dá sa použiť aj na puerilizmus, posttraumatická apoplexia, polyneuritída a radikulitída.Klinická funkcia: používa sa hlavne pri myasthenia gravis, pokojové štádium poliovírusu a jeho následky, aj pri polyneuritíde, funikulitída a senzomotorická bariéra spôsobená ochorením nervového systému alebo traumatizmom. Používa sa hlavne pri Alzheimerovej chorobe, má hlavnú funkciu pri demencii a dysmnézii spôsobenej organickým poškodením mozgu.
Galantamine Hydrobromide is the hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically or naturally from the bulbs and flowers of Narcissus and several other genera of the Amaryllidaceae family with anticholinesterase and neurocognitive-enhancing activities. Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing the concentration and enhancing the action of acetylcholine (Ach). Okrem toho, galantamine is a ligand for nicotinic acetylcholine receptors, which may increase the presynaptic release of Ach and activate postsynaptic receptors. This agent may improve neurocognitive function in mild and moderate Alzheimer' s disease and may reduce abstinence-induced cognitive symptoms that promote smoking relapse.
1.Galantamine hydrobromide powder is weak anticholinesterase drug through the blood-brain barrier, it is the role of the central nervous system.
2.Galantamine hydrobromide powder can make the neuromuscular recovery and improve the state of paralysis of various peripheral neuromuscular disorders.
3.Galantamine hydrobromide powder can treatment of a wide range of less toxic, and are well tolerated by patients.
4.Galantamine hydrobromide powder is mainly used in clinical treatment of sequelae of poliomyelitis (polio), muscular dystrophy and myasthenia gravis.
5.Galantamine hydrobromide powder can also be used for children with cerebral palsy, traumatic sensorimotor disorder, polyneuritis and radiculitis etc.
