Naphazoline (in the hydrochloride form) is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictorwith a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in thearterioles of the conjunctiva to produce constriction, resulting in decreased congestion.
It is used for the treatment of colds, acute en chronische rhinitis, allergische conjunctivitis, allergische en inflammatoire neusverstoppingsembolie. Lokaal langdurig gebruik kan leiden tot een vermindering van de bloedstroom op medicatiegebied, waardoor de weerstand afneemt , en resulteert in superinfectie. It can not be taken orally. Dropping excess liquid or high concentrations can cause poisoning. Care should be taken, especially in children. Infants, hypertensie, hyperthyroidism patients should take with caution, atrophic rhinitis patients are banned. The interval time of dropping , is preferably not less than 4 naar 6 uur.
