Rifaximin is an antibiotic that inhibits RNA synthesis and acts as a PXR (pregnane-X-receptor) activator. The compound is a derivative of rifamycin that has been shown to act strongly against Enterococcus, Streptococcus andStaphylococcus, with less activity against Enterobacteriaceae. Rifaximin has been used in a variety of gastrointestinal and intestinal epithelial cell studies.
1. Rifaximin as a gut antibiotic, rifamycin derivatives applicable to acute and chronic intestinal infections caused by Gram-positive bacteria and negative bacteria, aerobic and anaerobic bacteria, diarrhea syndrome, encefalite, hepatic coma.
2. Rifaximin Is a highly effective and low toxicity intestinal antibiotics.
