Tafluprost (trade names Taflotan by Santen Pharmaceutical, Zioptan by Merck in the US and Saflutan by Mundipharma in Australia) is a prostaglandin analogue. It is used topically (as eye drops) to control the progression of open-angle glaucoma and in the management of ocular hypertension, alone or in combination with other medication. It reduces intraocular pressure by increasing the outflow of aqueous fluid from the eyes.
Tafluprost is a prodrug of the active substance, tafluprost acid, a structural and functional analogue of prostaglandin F2α (PGF2α). O ácido tafluprost é um agonista seletivo do receptor da prostaglandina F, aumentando a saída de fluido aquoso dos olhos e, assim, diminuindo a pressão intraocular. Outros análogos de PGF2α com o mesmo mecanismo incluem latanoprost e travoprost.
