Thymosin β4 ubiquitous est, 43-amino acidic polypeptide cum hypothetica pondere 4.9 kDa.It valde conservatur per species, et invenitur in omnibus fibris et generibus cellularum exceptis cellulis sanguineis rubris. Thymosin β4 est dapibus multifunctionalis qui cellam migrationem promovet, caulis cellula cooptatione et differentia, proteste productio, et expressio diversorum generum regulatorii, ut laminin-332, fibrnectin, zyxin, VEGF, matrix metalloproteases, hepatocyte incrementum factor, et antioxidative enzymes (Mensa 1). Is inflammationem inhibet, microbial incrementum, cicatrix formationem (reducendo gradu myofibroblasts), et apoptosis, cellulae a cytotoxic dampnum et protegit, inter glutamate neuronal toxicity.Thymosin β4 ligat ad G-actin, cuneos actin polymerization, et coreleased cum factor XIIIa per platelets, suadet momenti in vulnere sanitatem.
