チモシンβ4は遍在しています, 43-の分子量を有するアミノ酸酸性ポリペプチド 4.9 kDa.種を超えて高度に保存されています, 赤血球を除くすべての組織および細胞型に存在します。. チモシン β4 は細胞遊走を促進する多機能タンパク質です, 幹細胞の動員と分化, プロテアーゼの生産, そしてさまざまな調節遺伝子の発現, such as laminin-332, fibronectin, zyxin, VEGF, matrix metalloproteases, hepatocyte growth factor, and antioxidative enzymes (Table 1). It inhibits inflammation, microbial growth, scar formation (by reducing the level of myofibroblasts), and apoptosis, and protects cells from cytotoxic damage, including glutamate neuronal toxicity.Thymosin β4 binds to G-actin, blocks actin polymerization, and is coreleased with factor XIIIa by platelets, suggesting its importance in wound healing.
