Трепростинил, продается под торговой маркой Ремодулин для инфузий., Оренитрам для приема внутрь, и Тывасо для ингаляций, — сосудорасширяющее средство, которое применяется для лечения легочной артериальной гипертензии. Трепростинил — синтетический аналог простациклина. (ЗГУ2).Трепростинил был одобрен для использования в США в мае. 2002.
The drug can be given in various forms: IV, subcutaneous injection, oral inhalation, as well as oral extended-release tablets. The subcutaneous administration tends to be very painful.
Treprostinil is indicated for the treatment of pulmonary arterial hypertension in people with NYHA Class II-IV symptoms to diminish symptoms associated with exercise.It may be administered as a continuous subcutaneous infusion or continuous intravenous infusion; однако, because of the risks associated with chronic indwelling central venous catheters, including serious blood stream infections, continuous intravenous infusion should be reserved for patients who are intolerant of the subcutaneous route, or in whom these risks are considered warranted. This medication is also available in inhaled and tablet forms.
