| Product Name |
Triptorelin Acetate |
| CAS NO. |
140194-24-7 |
| MF |
C64H82N18O13 |
| MW |
1311.45 |
| EINECS NO. |
N/A |
| Puritas |
99% |
| Aspectus |
White freeze dried powder |
| Repono |
Copia apud -20°C |
Triptorelin is a gonadotropin-releasing hormone agonist used as the acetate or pamoate salts. Adsidua excitanda pituitam, it decreases pituitary secretion of gonadotropins luteinizing hormone and follicle stimulating hormone. Sicut alii GnRH agonists, triptorelin adhiberi potest in curatione carcinomata hormona-responsiva, sicut prostatae cancer vel carcinomata sua, praematurae pubertatis, estrogen-dependens conditionibus, quam in reproduction adiuvisti. Triptorelin is marketed under the brand names Decapeptyl and Diphereline and Gonapeptyl.
Triptorelin,et decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), est gonadotropin-hormona agonist (GnRH agonist) usus est ut acetate vel pamoate sales. Adsidua excitanda pituitam, pituitariam secretionem decrescit gonadotropins hormone luteinizing (LH) et folliculus movens hormone (FSH). Sicut alii GnRH agonists, triptorelin adhiberi potest in curatione carcinomata hormona-responsiva, sicut prostatae cancer vel carcinomata sua, praematurae pubertatis, estrogen-dependens conditionibus (ut endometriosis fibroids vel vteri), quam in reproduction adiuvisti. It is also used as therapy in cases of gender dysphoria.
Triptorelin is a GNRH agaonist shown to inhibit estradiol-induced cancer cell proliferationIn vivo.
1. Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GNRHR-I expression of female rats, especially in late-growing follicles.
2. Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins.
3. Triptorelin may be used in the treatment of hormone-responsive cancers such as breast cancer or prostate cancer, praematurae pubertatis, estrogen-dependens conditionibus, and assisted reproduction.
una immunditia (HPLC): 1.0%max
Amino Acidum Compositio: ± X% speculationis
Peptide Content (N%): ≥80.0%
Aqua Content(Carolus Fischer): ≤6.0%
Triptorelin Acetate Acetate Content (HPIC): ≤15.0%
Triptorelin Acetate MS(ESI): Congruunt
Triptorelin Acetate Mass Balance: 95.0~105.0%
Triptorelin Acetate Specific Rotation (20/D): -65.0～-75.0°(c=0.5 1% HAc)
