Buserelin Acetate CAS:68630-75-1

Buserelin, onder andere onder die handelsnaam Suprefact verkoop word, is 'n medikasie wat hoofsaaklik gebruik word in die behandeling van prostaatkanker en endometriose. Dit word ook gebruik vir ander aanduidings soos die behandeling van premenopousale borskanker, uteriene fibroïede, en vroeë puberteit, in geassisteerde voortplanting vir vroulike onvrugbaarheid, en as deel van transgender hormoonterapie.Daarbenewens, buserelin is used in veterinary medicine.The medication is typically used as a nasal spray three times per day, but is also available for use as a solution or implant for injection into fat.

Side effects of buserelin are related to sex hormone deprivation and include symptoms of low testosterone levels and low estrogen levels such as hot flashes, sexual dysfunction, vaginal atrophy, and osteoporosis.Buserelin is a gonadotropin-releasing hormone agonist (GnRH agonist) and works by preventing the production of sex hormones by the gonads.It can lower sex hormone levels by about 95% in both sexes.Buserelin is a peptide and an analogue of GnRH.

Etilamide; HOE-766; HOE-766A; ICI-123215; S-746766; D-Ser(tBu)⁶EA¹⁰-LHRH; 6-[O-(1,1-Dimethylethyl)-D-serine]-9-(N-etiel-L-prolinamide)-10-deglycinamide-LHRH (pig)