Dermorphin is a peptide expressed by the frog venom skin glands with a potent opiate-like activity on mu-type opioid receptors, which have potent depressive and analgesic effects. Dermorphin may also have effects on pulmonary ventilation and pituitary hormone release.
Dermorphin est hepta-peptide separata primum a cortice ranarum Americanarum meridionalis ad genus Phyllomedusae pertinentium.. Peptida opioidis naturalis est quae agonista magna cum potentia et selectivity receptoribus opioidorum mu ligat..
Dermorphin est de 30-40 times more potent than mor-phine but theoretically may be less likely to produce drug tolerance and addiction (propter altitudinem potentiae). Sequentia acidorum amino dermorphin est H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2.
Dermorphin in hominibus vel aliis mammalibus non invenitur et peptides acido D-amino similes tantum in bacteria inveniuntur., amphibiorum et ostreis. Dermorphin in his fieri videtur per insolitam modificationem posttranslationalem ab amino acido isomerase factam.. Hic processus insolitus necessarius est quia D-alanine in hoc peptide non est apud 20 amino acida in genetica codice codeta et sic peptide more solito ab enodationibus in organismi organismi perstringi non potest..
Dermorphin is a natural heptapeptide μ-opioid receptor (MOR) agonist found in amphibian skin. Dermorphin can be used to suppress neuralgia.Dermorphin has been illegally used in horse racing as a performance-enhancing drug. Ob dermorphin scriptor painkilling actio, equi tractari dermorphin currere durius quam aliter
