Dehidroepiandrosteroon/dehidroepiandrostenedion (DHEA, meer korrek didehydroepiandrosterone), ook bekend as androstenolone sowel as 3β-hidroksiandrost-5-en-17-one of 5-androsten-3β-ol-17-one, is 'n belangrike endogene steroïedhormoon. In sy farmaseutiese geneesmiddelvorm word dit prasteroon genoem (INN). Dit is die volopste sirkulerende steroïedhormoon by mense, by wie dit in die byniere geproduseer word, die gonades, en die brein, waar dit hoofsaaklik funksioneer as 'n metaboliese intermediêre in die biosintese van die androgeen en estrogeen geslagsteroïede. Egter, DHEA het ook 'n verskeidenheid potensiële biologiese effekte in eie reg, binding aan 'n reeks kern- en seloppervlakreseptore, en dien as 'n neurosteroïed.
In middeljarige mans, geen statisties beduidende effek van DHEA-aanvulling op maer liggaamsmassa nie, sterkte, of testosteroonvlakke is gevind in 'n gerandomiseerde placebo-beheerde proef.
'N Klein studie het voorgestel dat DHEA-aanvulling geassosieer word met verhogings in gratis (maar nie totaal nie) testosterone levels.In women with adrenal insufficiency and the healthy elderly there is insufficient evidence to support the use of DHEA.
Dehydroepiandrosterone (DHEA) is a natural hormone produced by the adrenal gland, and many bodybuilders are using DHEA to gain a competitive advantage. Recent studies have now shown that supplements enhance lean muscle mass and minimize body fat and compare with natural steroids.
DHEA is used to slow down or reverse aging, improve the thinking ability of the elderly, slow down the progress of Alzheimer’s disease. Athletes and others use DHEA to increase muscle mass, strength and energy. But DHEA’s use is prohibited by the National University Sports Association (NCAA). DHEA word ook deur mans gebruik vir erektiele disfunksie (ED), as well as healthy women and women who have low levels of certain hormones to improve health and sex behavior.
