z Elcatonu
Alias:Calcinil,Carbicalcin,karbokalcitonín,z Elcatonu, elcitonín, Turbocalcin
CAS NO. : 60731-46-6
EINECS : 262-393-7
MF : C148H244N42O47
MW : 3363.82
Vzhľad : Biely prášok
Čistota : 98%
stupňa : Farmaceutická trieda
Obsah peptidov(od %N): ≥ 80 %
Obsah vody(Karl Fischer): ≤ 8,0 %
Obsah acetátu(pomocou HPLC): ≤12.0%
Aminokyselinové zloženie: ±10% of theoretical
Čistota(pomocou HPLC): 98.0%min.
Jediná nečistota(pomocou HPLC): 0.5%max.
Skúška(Bezvodý, Bez kyseliny octovej): 95.0~105,0 %
čs: Konzistentné
Skladovanie: Cool dry place(-20℃, away from the light)
Použitie : Elcatonin is used for Hypercalcemia, osteoporosis.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. Okrem toho, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. Okrem toho, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Obsah vody(Karl Fischer) :≤ 10,0 %
Obsah acetátu(pomocou HPLC) :≤ 15,0 %
Aminokyselinové zloženie :±10% of theoretical
Čistota (pomocou HPLC) :≥98,0 %
Jediná nečistota(pomocou HPLC) :≤ 1,0 %
Obsah peptidov(od %N) :≥ 80 %
Skúška(Bezvodý, Bez kyseliny octovej ) :95.0~105,0 %
Bakteriálne endotoxíny :≤5EU/mg
