Elcatonin
Псевдоним:Calcinil,Carbicalcin,Carbocalcitonin,Elcatonin, Elcitonin, Turbocalcin
CAS №. : 60731-46-6
EINECS : 262-393-7
MF : C148H244N42O47
MW : 3363.82
Външен вид : Бял прах
Чистота : 98%
Степен : Фармацевтичен клас
Съдържание на пептиди(by %N): ≥80%
Водно съдържание(Карл Фишер): ≤8,0%
Съдържание на ацетат(чрез HPLC): ≤12,0%
Аминокиселинен състав: ±10% от теоретичната
Чистота(чрез HPLC): 98.0%мин.
Единична примес(чрез HPLC): 0.5%макс.
Анализ(By Anhydrous, Acetic Acid-free): 95.0~105,0%
MS: Последователен
Съхранение: Cool dry place(-20℃, away from the light)
Използване : Elcatonin is used for Hypercalcemia, остеопороза.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. Освен това, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. Освен това, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Водно съдържание(Карл Фишер) :≤10,0%
Съдържание на ацетат(чрез HPLC) :≤15,0%
Аминокиселинен състав :±10% от теоретичната
Чистота (чрез HPLC) :≥98,0%
Единична примес(чрез HPLC) :≤1,0%
Съдържание на пептиди(by %N) :≥80%
Анализ(By Anhydrous, Acetic Acid-free ) :95.0~105,0%
Bacterial Endotoxins :≤5EU/mg
