Estradiol CAS:50-28-2

(1). Estradiol being a sex hormone. With alpha, beta, two types of alpha physiological function is strong. Steiner, winter was extracted from the horse urine pregnancy, moreover also can cause from the urine, placenta, pig ovary, ens. There is also a male horse testis or urine. Because it has the very strong sex role, so that it or its ester is, in fact, ovarian secretion of the sex hormones of the most important. Estradiol benzoate is decided to one of the international unit of sex hormone titer standard substance and used.

(2). Die menstruele siklus by vroue behels voorspelbare variasies in die vlakke van verskeie hormone, met oestradiol as een van hulle. Dit is betrokke by die ovulasieproses en berei die binnekant van die baarmoeder voor vir inplanting, moet die eiersel bevrug word. Sekere toetse wat op bobbejane en ander primate gedoen is, het aangedui dat sy hormoon ook 'n voortdurende rol speel in die handhawing van 'n swangerskap, help om dit vir die volle swangerskapsperiode te hou.

Female reproduction:In the female, estradiol acts as a hormone for tissue of the reproductive organs, supporting the lining of the vagina, the cervical glands, the endometrium, and the lining of the fallopian tubes. It enhances growth of the myometrium. Estradiol appears necessary to maintain oocytes in the ovary. During the menstrual cycle, estradiol produced by the growing follicle triggers, via a positive feedback system, the hypothalamic-pituitary events that lead to the luteinizing hormone surge, inducing ovulation. In the luteal phase, oestradiol, in conjunction with progesterone, prepares the endometrium for implantation. During pregnancy, estradiol increases due to placental production. In baboons, blocking of estrogen production leads to pregnancy loss, suggesting estradiol has a role in the maintenance of pregnancy. Research is investigating the role of estrogens in the process of initiation of labor. Actions of estradiol are required before the exposure of progesterone in the luteal phase.