Finasteride
CAS: 98319-26-7
Analysera: 99%
Utseende: Vitt eller benvitt kristallpulver
Molekylformel: C23H36N2O2
Molekylvikt: 372.5441
Densitet: 1.066g/cm3
Kokpunkt: 576.61°C kl 760 mmHg
Flampunkt: 177.448°C
Ångtryck: 0mmHg vid 25°C
Användande: Det är det 5 alfa – reduktashämmare som kan hämma testosteron att omvandlas till DHT. Används även för behandling av hyperplasi i prostata. Finasteride är en 4:a– aza-steroidförening som är en specifik hämmare av metabolismen av testosteron inom dihydrotestosteron blir starkare under celltyp II-enzymet 5a-reduktas. Den förstorade prostata som kallas benign prostatahyperplasi eller prostata beror på omvandlingen av testosteron till dihydrotestosteron.
Finasteride är ett populärt läkemedel mot androgen som tillverkas av Merck, oftast känd som antingen Proscar eller Propecia. Baserat på progesteronskelettet, Finasteride belongs to a class of medications known as 5alpha-reductase inhibitors and as such is used for the treatment revolving around type 2 5-AR based occurrences.
This is important for performance enhancers as DHT based anabolic steroids have specific side-effects that may occur that can largely be remedied with the use of a 5-AR inhibitor such as Finasteride. As a type 2 5-AR inhibitor Finasteride was designed for the purpose of treating hair-loss, prostate enlargement, as well as prostate cancer.
Finasteride is very common among those who supplement with anabolic steroids yet fear hair-loss but there are important things you need to understand before you consider Finasteride use. As an androgen suppressor Finasteride can seriously inhibit the gains made while on cycle, severely and on that basis it is not highly recommended for on-cycle hair preservation.
Propecia (finasteride) is used to treat male pattern baldness (androgenic alopecia) hos män. Oral use though will reduce DHT levels systemically, which may adversely affect training and sex drive.
It is also used in combination with doxazosin in the treatment of benign prostatic hyperplasia (BPH).] Finasteride is an orally active testosterone Type II 5-alpha reductase inhibitor, inhibiting the enzyme that converts testosterone to dihydrotestosterone (DHT).
Topically (on the scalp itself) it is of some effect in minimizing further hair loss. In combination with Nizoral and spironolactone (which smells awful, by the way) it can actually reverse loss moderately.
For use in cycles with testosterone, I don't think it is bad at all. Man vill helt enkelt inte ha mindre DHT än normalt. När mängden testosteron i systemet ökar, mängden finasterid som behövs för att hålla nivåerna nere till normala ökningar. anser jag 5 mg/dag rimligt på gram per vecka nivå, och proportionellt mindre vid lägre doser av testosteron.
| Specifik rotation |
-56°~-60° |
-58.2° |
|
Identifiering |
OCH |
Matchar med arbetsstandard |
Följer |
| HPLC |
|
Löslighet |
Lättlöslig i kloroform och alkohol; Mycket svagt löslig i vatten |
Anpassa |
|
Tungmetaller |
≤10 ppm |
<10 ppm |
|
Vatten |
≤0,3 % |
0.22% |
|
Rester vid antändning |
≤0,1 % |
0.05% |
|
Relativt material |
Max förorening≤0,5 % |
0.36% |
| Total förorening≤1,0 % |
0.52% |
| Analysera |
98.5~101,0 % |
99.48% |