Griseofulvina CAS:126-07-8

Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect of the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy.

Griseofulvin has inhibitory effect to psoriasis skin fungus, Contains a list of the skin ringworm fungi genera,ringworm fungi genera and microspore bacteria. Of tinea versicolor bacterium, white beads bacterium and bacteria is invalid. This product on bacteriostasis, effective for vigorous growth of fungi.