Nome do produto:(+)-Griseofulvina
Griseofulvina CAS:126-07-8
Griseofulvina MF:C17H17ClO6
Griseofulvin MW:352.77
Griseofulvina EINECS:204-767-4
Pureza da Griseofulvina:99%
Aparência da Griseofulvina:pó amarelo claro
Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect of the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy.
Griseofulvin has inhibitory effect to psoriasis skin fungus, Contains a list of the skin ringworm fungi genera,ringworm fungi genera and microspore bacteria. Of tinea versicolor bacterium, white beads bacterium and bacteria is invalid. This product on bacteriostasis, effective for vigorous growth of fungi.
| Itens de teste |
Especificação |
Resultados do teste |
| Características |
A yellowish-white,microfine powder |
yellowish-white,microfine powder |
| Ponto de fusão |
220ºC About 220ºC |
218.4ºC-219.4ºC |
| Rotação óptica específica |
+354o~+364o |
+356ó |
| Identificação |
Atende aos requisitos |
Atende aos requisitos |
| Check-up Particles size |
Atende aos requisitos |
Atende aos requisitos |
| Acidez |
0.25g consumed 0.02mol/l NaOH not more intensely coloured than reference solution Y4 |
0.6ml |
| Clarity and colour of solution |
The solution is clear and not more intensely coloured than reference solution Y4 |
Y5~Y6
Clear Y5~Y6 |
| Matter soluble in petroleum spirit |
≤0,2% |
0.1% |
| Cinza sulfatada |
≤0,2% |
0.1% |
| Substâncias relacionadas |
-Cl:<0.60 -H<0.15 |
-Cl:0.48-H:0.04 |
| Perda na secagem |
≤1,0% |
0.1% |
| Abnormal toxicity |
Atende aos requisitos |
Atende aos requisitos |
| ensaio(on the anhydrous substance) |
97.0%~102,0% |
98.3% |
| Conclusão |
The above certificate of analysis is in compliance with BP/EP,meets the standard requirements. |
