Leuprorelin CAS:53714-56-0

levprorelin, also known as leuprolide, is a manufactured version of a hormone used to treat prostate cancer, rak dojke, endometrioza, maternični fibroidi, and early puberty, to perform chemical castration of violent sex offenders, or as part of transgender hormone therapy.It is given by injection into a muscle or under the skin.

Common side effects include hot flashes, unstable mood, trouble sleeping, glavoboli, and pain at the site of injection.Other side effects may include high blood sugar, alergijske reakcije, and problems with the pituitary gland. Use during pregnancy may harm the baby.Leuprorelin is in the gonadotropin-releasing hormone (GnRH) analogue family of medications.It works by decreasing gonadotropin and therefore decreasing testosterone and estradiol

Leuprorelin se lahko uporablja pri zdravljenju raka, ki se odziva na hormone, kot sta rak prostate in rak dojke. Lahko se uporablja tudi za stanja, ki so odvisna od estrogena, kot so endometrioza ali maternični fibroidi.

Lahko se uporablja za prezgodnjo puberteto pri moških in ženskah,in za preprečevanje prezgodnje ovulacije v ciklih nadzorovane stimulacije jajčnikov za in vitro oploditev (IVF). This use is controversial since the Lupron label advises against using the drug when one is considering pregnancy, due to a risk of birth defects.

It may be used to reduce the risk of premature ovarian failure in women receiving cyclophosphamide for chemotherapy