Leuprorelin CAS:53714-56-0

Leuprorelin, also known as leuprolide, is a manufactured version of a hormone used to treat prostate cancer, Brustkrebs, Endometriose, Uterusmyome, und frühe Pubertät, to perform chemical castration of violent sex offenders, or as part of transgender hormone therapy.It is given by injection into a muscle or under the skin.

Common side effects include hot flashes, unstable mood, trouble sleeping, Kopfschmerzen, and pain at the site of injection.Other side effects may include high blood sugar, allergische Reaktionen, and problems with the pituitary gland. Use during pregnancy may harm the baby.Leuprorelin is in the gonadotropin-releasing hormone (GnRH) analogue family of medications.It works by decreasing gonadotropin and therefore decreasing testosterone and estradiol

Leuprorelin kann zur Behandlung von hormonabhängigen Krebsarten wie Prostatakrebs und Brustkrebs eingesetzt werden. Es kann auch bei östrogenabhängigen Erkrankungen wie Endometriose oder Uterusmyomen eingesetzt werden.

Es kann bei vorzeitiger Pubertät sowohl bei Männern als auch bei Frauen eingesetzt werden,und zur Verhinderung eines vorzeitigen Eisprungs in Zyklen kontrollierter Stimulation der Eierstöcke für die In-vitro-Fertilisation (IVF). This use is controversial since the Lupron label advises against using the drug when one is considering pregnancy, due to a risk of birth defects.

It may be used to reduce the risk of premature ovarian failure in women receiving cyclophosphamide for chemotherapy