Имя: Levobupivacaine Base
Синонимы:1-Бутил-Н-(2,6-диметилфенил)-piperidine-2-carboxamide;Chirocaine;Левобупивакаин;(2С)-1-Бутил-Н-(2,6-диметилфенил)piperidine-2α-carboxamide;2′,6′-Pipecoloxylidide, 1-butyl-, L-(-)-;1-Бутил-Н-(2,6-dimet;;(2С)-1-Бутил-Н-(2,6-diMethylphenyl)-2-piperidinecarboxaMide
КАС:27262-47-1
МФ:C18H28N2O
МВт:288.43
Температура плавления:136-137°С
Химические свойства:White Solid
Использование :Local anaesthetic used for epidural and intrathecal anaesthesia.
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children. Compared to bupivacaine, левобупивакаин связан с меньшей вазодилатацией и имеет более длительную продолжительность действия.. It is approximately 13 percent less potent (by molarity) than racemic bupivacaine and has a longer motor block onset time.
Clinical Use
Compared to bupivacaine, левобупивакаин связан с меньшей вазодилатацией и имеет более длительную продолжительность действия.. It is approximately 13 percent less potent (by molarity) than racemic bupivacaine and has a longer motor block onset time.
Indications
Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children.
Contraindications
Levobupivacaine is contraindicated for IV regional anaesthesia (IVRA).
