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Actieve farmaceutische producten

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Productnaam: Methylprednisolone
Synoniemen: (6alfa,11bèta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione;11,17,21-trihydroxy-6-methyl-1,4-pregnadiene-3,20-dione;11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione;11-bèta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione;1-dehydro-6alpha-methylhydrocortisone;20-dione,11,17,21-trihydroxy-6-methyl-,(6alfa,11bèta)-pregna-4-diene-3;20-dione,11-bèta,17,21-trihydroxy-6-alpha-methyl-pregna-4-diene-3;20-dione,11bèta,17,21-trihydroxy-6alpha-methyl-pregna-4-diene-3
CAS: 83-43-2
MF: C22H30O5
Mw: 374.47
EINECS: 201-476-4
Productcategorieën: Miscellaneous Biochemicals;Biochemie;Hydroxyketosteroïden;Steroïden;Tussenproducten & Fijne chemicaliën;Farmaceutische producten;Steroïden en hormonen;API;MEDROL;Hormoon medicijnen
Dikte: 1.28 g/cm3
Smeltpunt: 228-237 °C (dec.)
Kookpunt: 571.8 °C bij 760 mmHg
Vlampunt: 313.7 °C
Verschijning: White to off-white crystalline powder

Methylprednisolone is one kind of white to off-white crystalline powder. And its IUPAC name is also called(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[A]phenanthren-3-one. It belongs to the classes of Miscellaneous Biochemicals; Biochemie; Hydroxyketosteroïden; Steroïden; Tussenproducten & Fijne chemicaliën; Farmaceutische producten. It is sparingly soluble in alcohol, in dioxane, and in methanol, enigszins oplosbaar in aceton, and in chloroform, and very slightly soluble in ether. It is practically insoluble in water.

Methylprednisolone provides relief for inflamed areas of the body. Het wordt gebruikt om een ​​aantal verschillende aandoeningen te behandelen, zoals ontstekingen (zwelling), ernstige allergieën, bijnier problemen, artritis, astma, bloed- of beenmergproblemen, oog- of gezichtsproblemen, lupus, huidaandoeningen, nierproblemen, colitis ulcerosa, en opflakkeringen van multiple sclerose. Methylprednisolone is a corticosteroid (cortisone-achtige medicijnen of steroïden). Het werkt op het immuunsysteem om zwelling te helpen verlichten, roodheid, jeuk, en allergische reacties.

The Classification Code of this chemical is Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-inflammatory; Antiemetics; Autonomic Agents; Central Nervous System Agents; Drug / Therapeutic Agent; Gastrointestinal Agents; Glucocorticoïde; Glucocorticoids; Hormones; Hormones, Hormone Substitutes, and Hormone Antagonists; Human Data; Immunosuppressant; Neuroprotective agents; Peripheral Nervous System Agents; Protective Agents.

Methylprednisolon e has a strong anti-inflammatory effect and a weak sodium retention effect. Its anti-inflammatory effect is 7 times that of cortisone; methylprednisolon e succinate sodium is a water-soluble prednisolon e derivative, which is transformed in the body It is methylprednisolon e, which can be injected, has a quick-acting effect, and has a medium maintenance time. It is the preferred medicine for the treatment of inflammation and allergies. Acetate is a suspension, which has a slow onset and lasting effect after injection. Methylprednisolon e is a moderately effective glucocorticoid. The effect is the same as that of prednisolon e, its anti-inflammatory effect is 3 times that of the latter, the glucose metabolism effect is 10 times stronger than that of hydrocortisone, and the water and sodium retention effect is weak, and there is no side effect of potassium excretion. Its acetate suspension is injected intramuscularly and intra-articularly, it decomposes and absorbs slowly, and it lasts for a long time. After intramuscular injection 6-8h, the average peak blood concentration is 14.8μg/L, which can be maintained for 11-17 dagen. . Its sodium succinate is water-soluble and can be injected intramuscularly or intravenously

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