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Nootropiques

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Nom N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamic acid
Synonymes Nooglutil; Nooglutyl; ONK 10
Formule moléculaire C11H12N2O6
Poids moléculaire 268.22
Numéro de registre CAS 112193-35-8

Nooglutyl is a nootropic agent being studied at the Research Institute of Pharmacology, Russian Academy of Medical Sciences as a potential treatment for amnesia.In animal models, it has a variety of central nervous system effects.

Experiments on rats demonstrate that nooglutyl exhibits pronounced vestibular-protective properties and by its antimotion activity does not rank below classic vestibular protectors, such as scopolamine and diprazine. Electrophysiological experiments on cats show that nooglutyl alters spontaneous activity in 80% of cortical neurons (somatosensory zone I and area 5 of the parietal association cortex) and considerably weakens effects caused by motion sickness: activation of single unit activity of somatosensory zone I and inhibition of neuron responses to somatic stimulation. This property of the preparation is believed to form the basis of its antimotion effect.

1. Nooglutyl has glutamatergic effects is a highly active drug in treating disturbances of memory and learning, protecting against ischemic neuronal damage and brain injury. It has been demonstrated to have a stronger effect on glutamate receptors than Noopept.

2. Better for Memory Creation and Retention. Nooglutyl powder has been determined to have effective and potent nootropic properties.

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