Butylscopolamine bromide is pharmceutical material for peripheral anticholinergic drugs which can smooth muscle spasm, ease the gastrointestinal tract, bile duct and urinary tract and inhibit peristalsis.
Butylscopolamine bromide applies to the stomach, duodenum, colon fiber endoscopic examination as the operative preparation, so it can be used for the treatment of gastrointestinal spasm, biliary Colic, renal colic or gastrointestinal peristalsis, such as hyperthyroidism
1. Its primary use is for the treatment of post-operative nausea and vomiting, sea-sickness, leading to use by scuba divers.
2. Scopolamine is used as an adjunct anesthetic in trauma surgery. Light anesthesia is required to keep the patient hemodynamically stable, and this increases risk of awareness. Scopolamine decreases awareness and recall.
3. Scopolamine has been tested as a topical treatment for Aquagenic pruritus and was shown in several cases to be effective.
4. The drug has been reported as used by astronauts including those on Skylab for the treatment of motion sickness
5. Transdermal scopolamine patches are sometimes used to help control excessive saliva and drooling in patients with ALS
6. Scopolamine is also used for mild sedation and saliva management in end-of-life care as an adjunct to other comfort medications.
7. In October 2006, researchers at the US National Institute of Mental Health found that scopolamine reduced symptoms of depression within a few days, and the improvement lasted for at least a week after switching to a placebo.
8. Intravenously administered scopolamine has been found to be effective
