Estanolona CAS: 521-18-6

Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone. The enzyme 5α-reductase catalyzes the formation of DHT from testosterone in certain tissues including the prostate gland, seminal vesicles, epididymides, pele, hair follicles, liver, and brain. This enzyme mediates reduction of the C4-5 double bond of testosterone. Relative to testosterone, DHT is considerably more potent as an agonist of the androgen receptor (RA).

Stanolone is available in pharmaceutical formulations for medical use as an androgen or anabolic-androgenic steroid. It is used mainly in the treatment of male hypogonadism. When used as a medication, dihydrotestosterone is referred to as androstanolone or as stanolone, and is sold under brand names such as Andractim among others. The availability of pharmaceutical DHT is limited; it is not available in the United States or Canada, but is available in certain European countries. The available formulations of DHT include buccal or sublingual tablets, topical gels, e, as esters in oil, injectables like dihydrotestosterone propionate and dihydrotestosterone valerate.

Stanolone can be used as pharmaceutical material. Its main function is to promote metabolism. Anabolic effects include growth of muscle mass and strength, increased bone density and strength, and stimulation of linear growth and bone maturation. It doesn't metabolize in the body long enough to make it to the muscles.

The main androgen which is secreted by the testes is of course testosterone. No entanto, in most of the body, the androgenic sign is not carried through by testosterone. In these tissues including brain (CNS), pele, genitals - practically everything but muscle - the active androgen is actually dihydrotestosterone (DHT).

Stanolone is use for chronic wasting disease, osteoporose, severe infection and trauma, burn, etc caused by the negative nitrogen balance, promote the growth of premature infants and immature, etc.. The fracture is not easy to heal. Hypercholesterolemia and postpartum depression can also be used.