نام: Teduglutide
شماره CAS. : 197922-42-2
دنباله: His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp
فرمول مولکولی: C164H252N44O55S
وزن مولکولی : 3752.28
خلوص: >98.0%
ظاهر: پودر سفید
منبع: مصنوعی
ظاهر: پودر لیوفیلیزه سفید
Teduglutide is a glucagon-like peptide-2 (GLP-2) آنالوگ. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology.
Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide is longer acting than endogenous GLP-2 as it is more resistant to proteolysis from dipeptidyl peptidase-4.
Teduglutide is a glucagon-like peptide-2 (GLP-2); بازسازی, maintenance, and repair of the intestine.
