Tianeptine sodium is primarily used for its mood boosting and anti-anxiety properties. This substance also has nootropic abilities in regards to individuals whose cognition is negatively impacted by mood disorders. It has the ability to improve focus and concentration in individuals who have poor attention spans as well.
Depressive illness devastates millions of lives. Tianeptine is a neuroprotective antidepressant that reverses the neuronal damage and lasting misery caused by chronic, uncontrolled stress. Tianeptine acts both as a non-sedating anti-anxiety agent and a non-stimulating mood-brightener. Uniquely in clinical medicine, tianeptine acts as a selective serotonin reuptake enhancer. Its puzzling efficacy as an antidepressant illustrates how little modern psychiatric medicine really understands about mind, mood and depression.
Tianeptine is chemically a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (то есть, AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Тианептин демонстрирует эффективность против серьезных депрессивных эпизодов (большая депрессия), сравним с амитриптилином, имипрамин и флуоксетин, но со значительно меньшим количеством побочных эффектов. Было показано, что он более эффективен, чем мапротилин, в группе людей с сопутствующей депрессией и тревогой.. Тианептин также проявляет значительные анксиолитические свойства и полезен при лечении ряда тревожных расстройств, включая паническое расстройство., о чем свидетельствует исследование, в котором те, кто вводил 35% CO2 газ (карбоген) при терапии пароксетином или тианептином наблюдались эквивалентные эффекты блокировки паники.. Как и многие антидепрессанты (включая бупропион, селективные ингибиторы обратного захвата серотонина, ингибиторы обратного захвата серотонина и норадреналина, моклобемид и многие другие.) it may also have a beneficial effect on cognition in people with depression-induced cognitive dysfunction.
Tianeptine sodium salt is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (то есть, AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
