Име:Ganirelix acetate
Тип:GMP peptides
Последователност:Ac-D-2-Nal-D-4-ClPhe-D-3-Pal-Ser-Tyr-D-Lys(В(NHEt)
CAS.NO:123246-29-7
Единична примес(HPLC):1.0%
Съдържание на пептиди(N%):80%(by %N)
Acid content(HPLC):15.0%
Mass balance:95.0~105,0%
MW :1570.4
Формула :C80H113N18O13Cl
Чистота(HPLC):98.0%
Външен вид:Бял прах
Аминокиселинен състав:10% of theetical
Water content(Карл Фишер):6.0%
Ganirelix is a synthetic decapeptide compound. Its acetate, Ganirelix Acetate, releasing hormone (GnRH) receptor antagonist. The amino acid sequence is: Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-Tyr-D-HoChemicalbookmoArg(9,10-Et2)-Leu-L-HomoArg(9,10-Et2)-Pro-D- Ala-NH2. Клинично, it is mainly used in women receiving assisted reproductive technology in controlled ovarian stimulation programs to prevent premature lutei nizing hormone peaks and to treat fertility disorders caused by this reason.
Ganirelix should not be used in women who are already pregnant, and because of this the onset of pregnancy must be ruled out before it is administered. Women using ganirelix should not breast feed, as it is not known whether ganirelix is excreted in breast milk.
