Nome do produto: Larazotide
Nº CAS:258818-34-7
Sequência:Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine
Fórmula Molecular: C32H55N9O10
Peso molecular: 725.83 g/mol
Especificação: 1mg/frascos
Pureza : 98% HPLC
Aparência: Pó Liofilizado Branco
Uso típico: Celiac Therapy
Embalagem Padrão: 10frascos/kits
Larazotide (POUSADA; also known as AT-1001; formulated as the salt with acetic acid, larazotide acetate) is a synthetic eight amino acid peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state. It is being studied in people with celiac disease.
Larazotide is an octapeptide whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae. It has the amino acid sequence GGVLVQPG, IUPAC condensed descriptor of H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH, and the systematic name glycylglycyl-eu-valyl-eu-leucyl-eu-valyl-eu-glutaminyl-eu-prolyl-glycine.
