CAS番号: 139755-83-2
化学式: C22H19N3O4
分子量: 389.4
コンテンツ: 99.5% クエン酸シルデナフィル, バイアグラ
溶解性: 水にわずかに溶ける, メタノール; エタノールに非常にわずかに溶ける, クロロホルム
外観: 白色の結晶性粉末
ストレージ: シェーディング, 密閉保存.
使用法: バイアグラ (クエン酸シルデナフィル) 勃起不全の治療に使用される薬です (インポテンス) in males and pulmonary arterial
高血圧 (PAH).
クエン酸シルデナフィル, sold as Viagra, Sildenafil is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, 勃起機能障害と早漏は非常に大幅に改善されました. 以上です 1500 さまざまな原因によるインポテンス早漏の原因を証明する文書,成功率が上であることは知っていました 80%, 確実な治療効果を発揮します, 以上のものを使用することで 20 世界中で何百万人もの人が, 長期安定性を証明, の安全性 25 に 60 前戯に必要な時間と一致するよう、数分間の作業が機能します。, 薬剤濃度が最も高くなる時間帯の時間調整を知る, 夫と妻の両方が満足のいく性生活を送れるように支援する.
The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.It acts by inhibiting cGMP-specific phosphodiesterase type 5 (PDE5), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.
As well as erectile dysfunction, sildenafil citrate is also effective in the rare disease pulmonary arterial hypertension. It relaxes the arterial wall, leading to decreased pulmonary arterial resistance and pressure. これ, 順番に, reduces the workload of the right ventricle of the heart and improves symptoms of right-sided heart failure. Because PDE5 is primarily distributed within the arterial wall smooth muscle of the lungs and penis, sildenafil acts selectively in both these areas without inducing vasodilation in other areas of the body. Pfizer submitted an additional registration for sildenafil to the United States Food and Drug Administration (FDA), and sildenafil was approved for this indication in June 2005. The preparation is named Revatio, to avoid confusion with Viagra, and the 20-mg tablets are white and round. Sildenafil joins bosentan and prostacyclin-based therapies for this condition.
Sildenafil is used to treat high blood pressure in the lungs (pulmonary hypertension). It works by relaxing and widening the blood vessels in your lungs which allows the blood to flow more easily. Decreasing high blood pressure in the lungs allows your heart and lungs to work better and improves your ability to exercise.